Childhood-onset systemic lupus erythematosus
WebMay 6, 2024 · Childhood-onset systemic lupus erythematosus (cSLE) only represents 20% of all SLE patients, and males with SLE only represent 10%. To study this rare SLE subset, males diagnosed with cSLE over a 30-year period were identified. Organ involvement, autoantibody production, hypocomplementemia, and kidney biopsy findings … WebStudies on the right ventricular dysfunction (RV) in systemic lupus erythematosus (SLE) patients are limited, particularly in the pediatric age group. The study aimed to identify subclinical RV alterations in childhood-onset SLE (c-SLE) using conventional and three-dimensional echocardiography (3DE).
Childhood-onset systemic lupus erythematosus
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WebFeb 27, 2024 · Systemic lupus erythematosus (SLE) is an autoimmune rheumatic disease that results from the interaction of multiple environmental, immunological and genetic factors, causing inflammation and ... WebJul 25, 2012 · Purpose: In juvenile onset systemic lupus erythematosus (JoSLE), evidence for the association between vitamin D status, lupus activity, and bone health is …
WebMar 13, 2024 · A 5–year follow-up of pulmonary function tests in childhood-onset systemic lupus erythematosus: a single-center retrospective study. Restricted access Brief Report First published Mar 13, 2024. A 5–year follow-up of pulmonary function tests in childhood-onset systemic lupus erythematosus: a single-center retrospective study ... WebBackground: To our knowledge there are no studies assessing anti-Ro/SSA and anti-La/SSB autoantibodies in a large population of childhood-systemic lupus erythematosus (cSLE) patients. Methods: This was a retrospective multicenter cohort study performed in 10 Pediatric Rheumatology services, São Paulo state, Brazil. Anti-Ro/SSA and anti-La/SSB …
WebT1 - Clinico-immunological profile and outcome of childhood systemic lupus erythematosus. AU - Kadiyala, Ramya. AU - Kini, Pushpa Gurudas. AU - Aroor, Shrikiran. AU - Kumar, Sandeep. AU - Moras, Karen. PY - 2024/1/1. Y1 - 2024/1/1. N2 - Introduction: Paediatric lupus is an autoimmune disorder most commonly affecting adolescent females. WebNational Center for Biotechnology Information
WebSystemic lupus erythematosus (SLE) is a rare, severe, multisystem autoimmune disorder. Childhood-onset SLE (cSLE) follows a more aggressive course with greater associated morbidity and mortality than adult-onset SLE. Its aetiology is yet to be fully elucidated. It is recognised to be the archetypal systemic autoimmune disease, arising from a ...
how to start out a college essayWebJan 18, 2024 · The purpose of this study is to evaluate the pharmacokinetics (PK) of multiple doses of Telitacicept in subjects with childhood-onset systemic lupus erythematosus (cSLE) on a background of standard of care therapy and explore the safety and efficacy of Telitacicept in patients with cSLE. how to start out a pestle and mortarWebSystemic lupus erythematosus, also known as SLE, or simply lupus, is a disease characterized by inflammation of — and damage to — the organs, skin and joints. The kidneys, heart, lungs and brain are the organs most commonly affected. Lupus affects each child and adult differently. The effects of the illness can range from mild to severe ... react layout childrenWebObjective There is a pressing need for high-quality, comprehensive research to describe the natural history, best treatments, access to care and disparities in care for patients with childhood-onset SLE (cSLE). Building on a previously published survey study of cSLE clinicians and researchers to describe research priorities in cSLE, the primary objective … react layouteffectWebObjective: To assess the familial occurrence of systemic lupus erythematosus (SLE) in a large Brazilian cohort. Methods: Consecutive patients with SLE were recruited and stratified according to age at disease onset into childhood-onset SLE or adult-onset SLE. Each patient was personally interviewed regarding the history of SLE across 3 generations … react layout routerWebDefinition. Systemic lupus erythematosus (SLE) diagnosed in individuals under the age of eighteen. Children frequently have multi-organ involvement and acute disease onset. … how to start out a dnd campaignWebObjective: Systemic lupus erythematosus (SLE) is a chronic systemic disease, which can involve multiple organs such as kidney, skin and brain. Lung is another organ that can be affected. A number of pulmonary complications including pleuritis, pneumonitis, infectious pneumonia, pulmonary haemorrhage, pulmonary hypertension and pneumothorax have … react layout page